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UBXN2B Antibody, Biotin conjugated

Datasheet
Code CSB-PA614827LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) UBXN2B Polyclonal antibody
Uniprot No.
Q14CS0
Target Names
UBXN2B
Alternative Names
NSFL1 cofactor p37 antibody; p37 antibody; p97 cofactor p37 antibody; UBX domain containing protein 2B antibody; UBX domain protein 2B antibody; UBX domain-containing protein 2B antibody; UBX2B_HUMAN antibody; UBXN2B antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human UBX domain-containing protein 2B protein (2-250AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis.
Gene References into Functions
  1. these results demonstrate that p37 phosphorylation on Serine-56 and Threonine-59 is important for Golgi disassembly at mitosis. PMID: 20875789
Subcellular Location
Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum. Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein Families
NSFL1C family
Database Links

HGNC: 27035

OMIM: 610686

KEGG: hsa:137886

STRING: 9606.ENSP00000382507

UniGene: Hs.155572

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